The relationship between mode of delivery and Attention Deficit Hyperactivity Disorder: a meta-analysis and systematic review

This meta-analysis suggests that C-section is associated with a moderately increased risk of ADHD in children. Both elective and emergency C-sections showed similar effects. However, limitations such as study heterogeneity, potential publication bias, and lack of genetic or biological mechanism data are to be acknowledged. Further research is needed to clarify causality and explore underlying mechanisms.

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Publication Details

Journal
PeerJ
Published
2026-01-16
DOI
https://doi.org/10.7717/peerj.20603
Primary Topic
Attention Deficit Hyperactivity Disorder
Type
article
Field-Weighted Citation Impact
0.00
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article

The relationship between mode of delivery and Attention Deficit Hyperactivity Disorder: a meta-analysis and systematic review

J. Cheng-Chung Wei, Xue Pan, Han Mei, Xinyu Li et al.
PeerJ
Attention Deficit Hyperactivity Disorder
article

The relationship between mode of delivery and Attention Deficit Hyperactivity Disorder: a meta-analysis and systematic review

J. Cheng-Chung Wei, Xue Pan, Han Mei, Xinyu Li, Zehao Zheng, Yue Qiu, Yao Zheng, Kaishan Hou
article en

Abstract

This meta-analysis suggests that C-section is associated with a moderately increased risk of ADHD in children. Both elective and emergency C-sections showed similar effects. However, limitations such as study heterogeneity, potential publication bias, and lack of genetic or biological mechanism data are to be acknowledged. Further research is needed to clarify causality and explore underlying mechanisms.

PeerJVol. 14
Shanxi Medical University (CN), Beijing University of Chinese Medicine (CN), Changzhi Medical College (CN), Hebei University of Chinese Medicine (CN)
Openalex Percentile: Top 87%
Attention Deficit Hyperactivity Disorder
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