Efficacy and safety of autologous adipose-derived stem cells combined with platelet-rich plasma for periodontal regeneration: a multicenter, randomized, open-label, parallel-group comparative trial
Co-transplantation of ASCs with PRP is a safe and effective approach for periodontal regeneration, offering a promising therapeutic strategy for the treatment of periodontitis.
Authors
- HIKARI YONEDA
- Yosuke Masubuchi
- Masaki Honda (ORCID: https://orcid.org/0000-0002-2539-7986)
- KEIKO WAKANA
- Tomohiro Morio
- Akio Mitani (ORCID: https://orcid.org/0000-0001-5427-411X)
- Morikuni Tobita (ORCID: https://orcid.org/0000-0001-7422-1920)
- Anna Arita (ORCID: https://orcid.org/0000-0002-7053-0336)
- Jun-ichiro Hayashi
- Shinya Murakami
- Kino-oka Masahiro
- Yorimasa Ogata
- Takeshi Kikuchi
- Yuki Suzuki
- Taku Toriumi
- Hiroshi Mizuno
- Jorge Luis Montenegro Raudales
- Kiyoshi Okada
Institutions
- Nihon University (JP)
- Aichi Gakuin University (JP)
- Juntendo University (JP)
- Nippon Dental University (JP)
- Juntendo University Hospital (JP)
- The University of Tokyo (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1016/j.reth.2026.101062
- Citations
- 1
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 41.56