Dose-guided individualized planning target volume margin optimization in nasopharyngeal carcinoma: a retrospective megavoltage computed tomography–based cumulative analysis

MVCT-based cumulative dose evaluation provides a more accurate assessment of the delivered dose than conventional geometric methods. Individualized, dose-driven PTV margin strategies may improve tumor coverage while minimizing OAR exposure, thereby advancing precision radiotherapy for NPC.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-16
DOI
https://doi.org/10.3389/fonc.2025.1727150
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Dose-guided individualized planning target volume margin optimization in nasopharyngeal carcinoma: a retrospective megavoltage computed tomography–based cumulative analysis

Wenheng Zheng, Y. Zhang, Changfei Gong, Longfei Xu et al.
Frontiers in Oncology
Advanced Radiotherapy Techniques
article

Dose-guided individualized planning target volume margin optimization in nasopharyngeal carcinoma: a retrospective megavoltage computed tomography–based cumulative analysis

Wenheng Zheng, Y. Zhang, Changfei Gong, Longfei Xu, Junming Jian, Changwei Luo, Xingxing Yuan
article en

Abstract

MVCT-based cumulative dose evaluation provides a more accurate assessment of the delivered dose than conventional geometric methods. Individualized, dose-driven PTV margin strategies may improve tumor coverage while minimizing OAR exposure, thereby advancing precision radiotherapy for NPC.

Frontiers in OncologyVol. 15
First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial Cancer Hospital (CN), Center for Personalized Cancer Treatment (NL)
Health Commission of Jiangxi Province
Openalex Percentile: Top 86%
Advanced Radiotherapy Techniques
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