Treatment Recommendations for Clinical Deterioration on the Wards: Development and Validation of Machine Learning Models

We found variability in the discrimination of ML models across tasks and model approaches for predicting lifesaving treatments in patients with clinical deterioration. Overall performance was high, and these models could be paired with early warning scores to provide clinicians with timely and actionable treatment recommendations to improve patient care.

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Publication Details

Journal
JMIR AI
Published
2026-01-16
DOI
https://doi.org/10.2196/81642
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment Recommendations for Clinical Deterioration on the Wards: Development and Validation of Machine Learning Models

Yonatan Mintz, MATTHEW M CHURPEK, Urmila Ravichandran, Madeline Oguss et al.
JMIR AI
Sepsis Diagnosis and Treatment
article

Treatment Recommendations for Clinical Deterioration on the Wards: Development and Validation of Machine Learning Models

Yonatan Mintz, MATTHEW M CHURPEK, Urmila Ravichandran, Madeline Oguss, L. Nezirova, L. Penumalee, Kyle A. Carey, Tonela Qyli, EMILY R GILBERT, Dana P Edelson, Majid Afshar, Sean T Tully, Eric Pulick, Nirav S Shah, Jamila K Picart
article en

Abstract

We found variability in the discrimination of ML models across tasks and model approaches for predicting lifesaving treatments in patients with clinical deterioration. Overall performance was high, and these models could be paired with early warning scores to provide clinicians with timely and actionable treatment recommendations to improve patient care.

JMIR AIVol. 5
Loyola University Medical Center (US), NorthShore University HealthSystem (US), University of Wisconsin–Madison (US), University of Michigan (US), University of Chicago (US), Northwestern Memorial Hospital (US), Evanston Hospital (US)
Reduced inequalities
Openalex Percentile: Top 86%
Sepsis Diagnosis and Treatment
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Treatment Recommendations for Clinical Deterioration on the Wards: Development and Validation of Machine Learning Models — Yonatan Mintz, MATTHEW M CHURPEK, et al. · JMIR AI (2026) | TGRS Research Map | TGRS