Natural Killer T cells promote cholestatic liver disease independent of antigen presentation by cholangiocytes

A subset of hepatic NKT cells contributes to cholestatic liver disease, and their activation is independent of CD1d antigen presentation on cholangiocytes.

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Publication Details

Journal
Hepatology Communications
Published
2026-01-16
DOI
https://doi.org/10.1097/hc9.0000000000000862
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Natural Killer T cells promote cholestatic liver disease independent of antigen presentation by cholangiocytes

Natalie Lie Berntsen, Anna Katharina Frank, Espen Melum, Kathrine Sivertsen Nordhus et al.
Hepatology Communications
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Natural Killer T cells promote cholestatic liver disease independent of antigen presentation by cholangiocytes

Natalie Lie Berntsen, Anna Katharina Frank, Espen Melum, Kathrine Sivertsen Nordhus, Enya Amundsen-Isaksen, Brian K. Chung, Jonas Øgaard, Thierry Claudel, Claudia Fuchs, Xiangxiang Jiang, Michael Trauner, Laura Valestrand
article en

Abstract

A subset of hepatic NKT cells contributes to cholestatic liver disease, and their activation is independent of CD1d antigen presentation on cholangiocytes.

Hepatology CommunicationsVol. 10(2)
Oslo University Hospital (NO), University of Oslo (NO), Medical University of Vienna (AT)
Openalex Percentile: Top 86%
Immune Cell Function and Interaction
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