Sialylation-immune-related lncRNA LINC01605 promotes tumor-infiltrating CD8+ T cell exhaustion and malignancy of clear cell renal cell carcinoma
Our findings reveal the role of sialylation-immune-related lncRNAs in the immunosuppressive tumor microenvironment and cancer progression in ccRCC, providing a new framework for predicting patient outcomes and therapeutic responses.
Authors
- Garry Huang (ORCID: https://orcid.org/0000-0002-1328-5055)
- Yanping Liang (ORCID: https://orcid.org/0009-0003-4471-9420)
- J. Wei (ORCID: https://orcid.org/0000-0001-5256-8851)
- Mingxiao Zhang (ORCID: https://orcid.org/0000-0002-4903-2025)
- Junjie Cen (ORCID: https://orcid.org/0000-0002-0980-7551)
- Zhenhua Chen
- Zheyu Ai
- Ziran Dai
- Hao Zhou
- Zihao Feng
- Junhang Luo
- Wei Chen
Institutions
- Sun Yat-sen University (CN)
- China-Japan Friendship Hospital (CN)
- Southern University of Science and Technology (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1744278
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00