Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee

Our data demonstrate that T-SIFK is generated by subchondral bone fracture and its repair reaction and suggest that fat necrosis of the bone marrow is involved in BML formation in T-SIFK and OA.

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Publication Details

Journal
Arthritis Research & Therapy
Published
2026-01-16
DOI
https://doi.org/10.1186/s13075-026-03733-w
Primary Topic
Bone and Joint Diseases
Type
article
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0.00
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article

Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee

Chiho Yoshinaga, Y. Okada, Jun Tomura, Takuya Yamamura et al.
Arthritis Research & Therapy
Bone and Joint Diseases
article

Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee

Chiho Yoshinaga, Y. Okada, Jun Tomura, Takuya Yamamura, Yuka Kenzaki, Haruka Kaneko, Muneaki Ishijima, Takako Negishi-Koga
article en

Abstract

Our data demonstrate that T-SIFK is generated by subchondral bone fracture and its repair reaction and suggest that fat necrosis of the bone marrow is involved in BML formation in T-SIFK and OA.

Arthritis Research & TherapyVol. 28(1)
Juntendo University (JP)
Good health and well-being
Openalex Percentile: Top 87%
Bone and Joint Diseases
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