Scoliosis correction in spinal muscular atrophy

Postoperative complications were less severe (CD 1 to 2) with preoperative DMA treatment. Coupled with DMA use, pulmonary function was stabilized after scoliosis surgery at almost seven years' follow-up. Improvements in hospital LOS and days intubated postoperatively are potential benefits of preoperative DMA treatment, serving to increase confidence to offering these major orthopaedic surgeries for patients with SMA. Improvements in outcomes may also reflect advances in surgical techniques and perioperative care over the study period. Further comparative studies are warranted to better isolate the specific impacts of DMA treatment.