Blastocystis hominis infection inducing gut microbiome dysbiosis and aggravating Parkinson’s disease symptoms: a case report

This case highlights the need to consider parasitic infections in patients with Parkinson's disease presenting with chronic diarrhea. While we hypothesize that B. hominis infection may transiently worsen Parkinson's disease symptoms through inflammatory or microbiota-mediated pathways, this remains speculative in the absence of microbiome sequencing or objective neurologic evaluation. Further studies integrating clinical, microbiological, and microbiome analyses are warranted.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-01-16
DOI
https://doi.org/10.1186/s13256-025-05763-5
Primary Topic
Parasitic Infections and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Blastocystis hominis infection inducing gut microbiome dysbiosis and aggravating Parkinson’s disease symptoms: a case report

Tala Charafeddine, Laila Al Akel, Walid Abdel Khalek, Serena Khoury et al.
Journal of Medical Case Reports
Parasitic Infections and Diagnostics
article

Blastocystis hominis infection inducing gut microbiome dysbiosis and aggravating Parkinson’s disease symptoms: a case report

Tala Charafeddine, Laila Al Akel, Walid Abdel Khalek, Serena Khoury, Loulewa Al Sayed, Philippe Attieh, Lama Al Akel, Emanuel-Youssef Dib, Karam Karam
article en

Abstract

This case highlights the need to consider parasitic infections in patients with Parkinson's disease presenting with chronic diarrhea. While we hypothesize that B. hominis infection may transiently worsen Parkinson's disease symptoms through inflammatory or microbiota-mediated pathways, this remains speculative in the absence of microbiome sequencing or objective neurologic evaluation. Further studies integrating clinical, microbiological, and microbiome analyses are warranted.

Journal of Medical Case ReportsVol. 20(1)
University of Balamand (LB)
Good health and well-being
Openalex Percentile: Top 83%
Parasitic Infections and Diagnostics
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