Skeletal muscle-kidney crosstalk in a cohort of critical illness survivors

In survivors of moderate to severe COVID-19 hospitalization, skeletal muscle mass was associated with eGFR, whereas sarcopenia per se was not independently associated with poor kidney function. These findings suggest the existence of a skeletal muscle-kidney crosstalk in this population.

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Publication Details

Journal
PLoS ONE
Published
2026-01-16
DOI
https://doi.org/10.1371/journal.pone.0339795
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
0.00

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article

Skeletal muscle-kidney crosstalk in a cohort of critical illness survivors

Lia Marçal, Linamara Rizzo Battistella, Leila Antonângelo, Geraldo F. Busatto et al.
PLoS ONE
Nutrition and Health in Aging
article

Skeletal muscle-kidney crosstalk in a cohort of critical illness survivors

Lia Marçal, Linamara Rizzo Battistella, Leila Antonângelo, Geraldo F. Busatto, Guilherme P. Santa-Catharina, Luis Yu, Dario R. Mondini, Dirce M. T. Zanetta, Carlos Alberto Peixoto de Carvalho, Heitor S. Ribeiro, for the HCFMUSP COVID-19 Study Group
article en

Abstract

In survivors of moderate to severe COVID-19 hospitalization, skeletal muscle mass was associated with eGFR, whereas sarcopenia per se was not independently associated with poor kidney function. These findings suggest the existence of a skeletal muscle-kidney crosstalk in this population.

PLoS ONEVol. 21(1)
Universidade de São Paulo (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
AstraZeneca, Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 87%
Nutrition and Health in Aging
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