Clinical Validation of a Simplified, Scrape-Free Collection Method for Multitarget Stool RNA Testing in Colorectal Cancer Screening

Our findings suggest that in-laboratory FIT performance may enhance the diagnostic accuracy of the mt-sRNA test. The in-laboratory method may also reduce inadequate sampling and improve patient ease of use.

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Publication Details

Journal
Journal of Clinical Gastroenterology
Published
2026-01-16
DOI
https://doi.org/10.1097/mcg.0000000000002336
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Validation of a Simplified, Scrape-Free Collection Method for Multitarget Stool RNA Testing in Colorectal Cancer Screening

Kimberly Kruse, Matthew A. Kinseth, Erica K. Barnell, Theodore R. Levin et al.
Journal of Clinical Gastroenterology
Colorectal Cancer Screening and Detection
article

Clinical Validation of a Simplified, Scrape-Free Collection Method for Multitarget Stool RNA Testing in Colorectal Cancer Screening

Kimberly Kruse, Matthew A. Kinseth, Erica K. Barnell, Theodore R. Levin, Aasma Shaukat, Ryan Ghannam, Samir Gupta
article en

Abstract

Our findings suggest that in-laboratory FIT performance may enhance the diagnostic accuracy of the mt-sRNA test. The in-laboratory method may also reduce inadequate sampling and improve patient ease of use.

Journal of Clinical Gastroenterology
Kaiser Permanente (US), Moore College of Art and Design (US), Oregon Health & Science University (US), Washington University in St. Louis (US), VA NY Harbor Healthcare System (US), Genex Systems (United States) (US), Human Longevity (United States) (US), New York University (US)
Openalex Percentile: Top 86%
Colorectal Cancer Screening and Detection
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Clinical Validation of a Simplified, Scrape-Free Collection Method for Multitarget Stool RNA Testing in Colorectal Cancer Screening — Kimberly Kruse, Matthew A. Kinseth, et al. · Journal of Clinical Gastroenterology (2026) | TGRS Research Map | TGRS