Unveiling Active Natural Products for the Therapy of Inflammatory Bowel Disease through Single-cell, Transcriptome, and Reverse NetworkPharmacology
This study provides a comprehensive understanding of the molecular mechanisms underlying IBD, identifies MMP2 as a key target, and highlights isoprincepin as a promising natural product for IBD therapy.
Authors
- C. S. Shang (ORCID: https://orcid.org/0000-0002-2800-1836)
- Jiaxin Zhou (ORCID: https://orcid.org/0000-0002-1664-3495)
- Yingying Zhang (ORCID: https://orcid.org/0000-0002-3117-2855)
- Na Tian
- Jianping Hu
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2026-01-08
- DOI
- https://doi.org/10.2174/0115734099420555251125065850
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00