Low PAPP-A Levels and Growth in Twin Pregnancies

Low PAPP-A levels were associated with BW ≤ 10th centile in one and both twins and its significant value as a risk marker was demonstrated. Higher PAPP-A MoM halves the risk of having at least one twin with low BW. Other maternal biophysical and biochemical indices did not seem to be predictive of low birthweight.

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Journal
Life
Published
2026-01-16
DOI
https://doi.org/10.3390/life16010149
Primary Topic
Pregnancy and preeclampsia studies
Type
article
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article

Low PAPP-A Levels and Growth in Twin Pregnancies

I. Pafilis, Christina Karasmani, Dimitrios Papageorgiou, Maria Simou et al.
Life
Pregnancy and preeclampsia studies
article

Low PAPP-A Levels and Growth in Twin Pregnancies

I. Pafilis, Christina Karasmani, Dimitrios Papageorgiou, Maria Simou, G. Daskalakis, Ioakeim Sapantzoglou, Angeliki Rouvali, Afroditi Pegkou, Afroditi Maria Kontopoulou, Panagiotis Antsaklis, Marianna Theodora, Athina Souka
article en

Abstract

Low PAPP-A levels were associated with BW ≤ 10th centile in one and both twins and its significant value as a risk marker was demonstrated. Higher PAPP-A MoM halves the risk of having at least one twin with low BW. Other maternal biophysical and biochemical indices did not seem to be predictive of low birthweight.

LifeVol. 16(1)
University of Ioannina (GR), National and Kapodistrian University of Athens (GR), Athens Naval & Veterans Hospital (GR)
Good health and well-being
Openalex Percentile: Top 87%
Pregnancy and preeclampsia studies
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