Statistically significant results from low-power analyses: A comedy of errors

Low-power statistically significant results may consist entirely of magnitude errors, sign errors, and type 1 errors with high risk of strong overestimation (double effect). Readers should beware positive results from low-power analyses.

Authors

Cyril Jaksic (ORCID: https://orcid.org/0000-0001-5835-3480)
PhDThomas Perneger
Christophe Combescure

Institutions

University Hospital of Geneva (CH)

Publication Details

Journal: Global Epidemiology
Published: 2026-01-16
DOI: https://doi.org/10.1016/j.gloepi.2026.100250
Primary Topic: Advanced Electrical Measurement Techniques
Type: article
Field-Weighted Citation Impact: 0.00

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article

Statistically significant results from low-power analyses: A comedy of errors

Cyril Jaksic, PhDThomas Perneger, Christophe Combescure

Jan 16, 2026

Global Epidemiology

Advanced Electrical Measurement Techniques

article

Statistically significant results from low-power analyses: A comedy of errors

Cyril Jaksic, PhDThomas Perneger, Christophe Combescure

January 16, 2026article en

Abstract

Global EpidemiologyVol. 11

University Hospital of Geneva (CH)

Openalex Percentile: Top 87%

Advanced Electrical Measurement Techniques

DOI Open Access PDF OpenAlex

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Statistically significant results from low-power analyses: A comedy of errors — Cyril Jaksic, PhDThomas Perneger, et al. · Global Epidemiology (2026) | TGRS Research Map | TGRS