Clinical Trials for Children and Adolescents With Cancer in Latin America
The improvement of childhood cancer outcomes has relied on clinical trials. The WHO's International Clinical Trials Registry Platform was searched for interventional clinical trials for children and adolescents with cancer in Latin America. Forty-seven trials were identified. Institutions were the primary sponsors for 38 (88.8%) trials, and 31 (65.9%) were conducted at a single site. Supportive care interventions (26, 55.3%) were more common than cancer-directed treatment trials. Thirteen (27.6%) trials had published results. Few trials were registered in Latin America. Strengthening research infrastructure and fostering collaborations are essential for equity in pediatric cancer research in the region.
Authors
- Michael S. B. Edwards (ORCID: https://orcid.org/0000-0001-9591-1242)
- Catrian Sotelo (ORCID: https://orcid.org/0000-0001-9005-9329)
- Guillermo Chantada (ORCID: https://orcid.org/0000-0002-9375-9336)
- Paola M. Friedrich (ORCID: https://orcid.org/0000-0002-5265-3113)
- Margit K. Mikkelsen (ORCID: https://orcid.org/0009-0005-1728-6070)
- Mackenzie Kelley
- Ryan R Lion
- Milena Villarroel
- Hanna Ravi
- Daniel C. Moreira
- Oscar González‐Ramella
- Carlos Rodriguez‐Galindo
Institutions
- Hospital Sant Joan de Déu Barcelona (ES)
- St. Jude Children's Research Hospital (US)
- Eastern Virginia Medical School (US)
- Garrahan Hospital (AR)
- Centro Hospitalario Pereira Rossell (UY)
- Hospital Luis Calvo Mackenna (CL)
- Center for Cancer and Blood Disorders (US)
- Hospital Civil de Guadalajara (MX)
- University of Colorado Denver (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1002/1545-5017.70136
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00