Effect of Direct-from-blood Bacterial Testing on Antibiotics Administration in Adults Presenting With Acute Infection: A Randomized Trial
Among adults with suspected infection receiving empiric intravenous vancomycin in the emergency department, use of direct-from-blood bacterial testing did not shorten the duration of intravenous vancomycin or antipseudomonal beta-lactam antibiotics.
Authors
- Laura J. Bobbitt (ORCID: https://orcid.org/0000-0003-2386-9318)
- Matthew W. Semler (ORCID: https://orcid.org/0000-0002-7664-8263)
- Mary Lynn Dear (ORCID: https://orcid.org/0000-0002-0215-9299)
- Halden Z. VanCleave (ORCID: https://orcid.org/0009-0003-9165-4420)
- Romney M. Humphries (ORCID: https://orcid.org/0000-0002-6568-156X)
- C. Schaeffer
- A. Lewis
- Connor Burns (ORCID: https://orcid.org/0009-0008-9365-3612)
- David C. Gaston (ORCID: https://orcid.org/0000-0002-7320-5635)
- Edward T. Qian (ORCID: https://orcid.org/0000-0002-1092-3533)
- T Rice (ORCID: https://orcid.org/0000-0002-7136-5408)
- Matthew A. Christensen (ORCID: https://orcid.org/0000-0002-6021-8680)
- Hamilton Wen
- George E. Nelson (ORCID: https://orcid.org/0000-0003-2701-1917)
- Andrea Mary Fletcher (ORCID: https://orcid.org/0000-0002-6089-0602)
- Adam Benedict Turner (ORCID: https://orcid.org/0000-0002-4485-6738)
- Joanna L. Stollings (ORCID: https://orcid.org/0000-0001-6792-1646)
- Benjamin Ereshefsky (ORCID: https://orcid.org/0000-0001-8165-5743)
- Austin Ing
- Matthew J. Rodgers
- Gabriel Kemp
- Alison Benton
- Allyson Hobbie
- Jakea Johnson
- Timothy Duff
- Sharon Glover
- Cheryl L Gatto
- Li Wang
- LaKeysha Wiggins
- Karen F Miller
- Geoff Mavrak
- Dan Albert
- Wesley H Self
- Kelly Moser
- Sabrina Shipman
- Shannon Pugh
- Adrienne Baughman
- Sheryl Mangrum
Institutions
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-12-13
- DOI
- https://doi.org/10.1093/cid/ciaf677
- Citations
- 2
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 2.64