Venous thromboembolism prophylaxis in adults hospitalised for psychiatric illness: an evidence-based clinical practice guideline developed using GRADE

Clinicians should not use parenteral pharmacological prophylaxis in adults hospitalised with psychiatric illness at low risk of VTE; and should consider using parenteral pharmacological prophylaxis for high-risk adults with no contraindications. Graduated compression stockings are not recommended in high-risk patients when parenteral pharmacological prophylaxis is contraindicated. These GRADE- based recommendations offer one of the first evidence-based practice guidelines for thromboprophylaxis decisions in psychiatric in-patient settings.

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Publication Details

Journal
International Journal of Clinical Pharmacy
Published
2026-01-16
DOI
https://doi.org/10.1007/s11096-025-02072-1
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Venous thromboembolism prophylaxis in adults hospitalised for psychiatric illness: an evidence-based clinical practice guideline developed using GRADE

Dolores Keating, Richard M. Duffy, Jennifer M.D. Hoblyn, Josie Jenkinson et al.
International Journal of Clinical Pharmacy
Venous Thromboembolism Diagnosis and Management
article

Venous thromboembolism prophylaxis in adults hospitalised for psychiatric illness: an evidence-based clinical practice guideline developed using GRADE

Dolores Keating, Richard M. Duffy, Jennifer M.D. Hoblyn, Josie Jenkinson, Fionnuala Ní Áinle, Audrey Purcell, Arnav Agarwal, Kathy Morgan, Aurelien Delluc, Aoife Carolan, Eric Roche, Sarah Garvey, Beverley J. Hunt, Joanne Flood, Ann Marie O′ Neill
article en

Abstract

Clinicians should not use parenteral pharmacological prophylaxis in adults hospitalised with psychiatric illness at low risk of VTE; and should consider using parenteral pharmacological prophylaxis for high-risk adults with no contraindications. Graduated compression stockings are not recommended in high-risk patients when parenteral pharmacological prophylaxis is contraindicated. These GRADE- based recommendations offer one of the first evidence-based practice guidelines for thromboprophylaxis decisions in psychiatric in-patient settings.

International Journal of Clinical Pharmacy
University College Dublin (IE), Royal College of Surgeons in Ireland (IE), University of Ottawa (CA), University of Alberta (CA), Guy's and St Thomas' NHS Foundation Trust (GB), Rotunda Hospital (IE), Beaumont Hospital (IE), Health Service Executive (IE), Mental Health Ireland (IE), King's College Hospital NHS Foundation Trust (GB), Adient (Ireland) (IE), Pennine Care NHS Foundation Trust (GB), St John of God Hospital (AU), Imperial College London (GB), Surrey and Borders Partnership NHS Foundation Trust (GB), Royal College of Psychiatrists (GB), McMaster University (CA)
McMaster University, Royal College of Surgeons in Ireland
Openalex Percentile: Top 88%
Venous Thromboembolism Diagnosis and Management
DOIOpen Access PDFOpenAlex
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