Multiplex autoantibody screening in pediatric type 1 diabetes: POC Blot vs. ELISA for gluten-related disorders
The POC blot assay demonstrates promising potential as a reliable and rapid screening tool for autoantibodies in pediatric patients with T1D and gluten-related disorders in resource-limited settings. While further validation is needed, these findings suggest that POC testing could facilitate earlier diagnosis and improve the clinical management of coexisting autoimmune conditions in this population.
Authors
- Mesfin Bekele
- Patricia Wusterhausen
- Adugna Boke Negussie
- Torsten Matthias
- Demise Mulugeta
- Deselegn Muleta
Institutions
- College of Medical Sciences (NP)
- CS Diagnostics (DE)
- The Medical Device (United Kingdom) (GB)
- Adama Science and Technology University (ET)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1648451
- Primary Topic
- Celiac Disease Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00