Curation of the Fasciola hepatica kinome as a resource for drug target discovery
These findings suggest that repurposing small-molecule PK inhibitors could be a good strategy for obtaining compounds to combat fascioliasis. The newly established F. hepatica kinome represents a resource for future target discovery.
Authors
- Simone Haeberlein (ORCID: https://orcid.org/0000-0002-1932-9696)
- Andreas J. Stroehlein (ORCID: https://orcid.org/0000-0001-9432-9816)
- Oliver Puckelwaldt (ORCID: https://orcid.org/0000-0003-2543-078X)
- Sagar Ajmera
Institutions
- Justus-Liebig-Universität Gießen (DE)
- Federal Institute for Risk Assessment (DE)
Publication Details
- Journal
- BMC Genomics
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1186/s12864-025-12513-w
- Primary Topic
- Helminth infection and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00