Demographic and prognostic landscape of upper urinary tract urothelial carcinoma: an analysis of a national cancer database

This large-scale analysis identifies the primary tumor site as a key prognostic factor in UC, with renal pelvis tumors demonstrating more favorable survival. The study also confirms the significant influence of comorbidity and tumor stage while uniquely highlighting that socioeconomic factors, such as income and insurance, are powerful predictors of outcome. These findings underscore the need for optimized, site-specific treatment strategies and concerted efforts to address healthcare inequities in the management of upper tract UC.