A swine model of severe chronic thromboembolic pulmonary hypertension induced by repeated pulmonary artery long suture injection
We developed a new and straightforward swine model of severe CTEPH with RV dysfunction by repeated injection of long sutures into the PA without the need for additional hits which may be valuable for preclinical research.
Authors
- P Mendes-Ferreira
- Aurélie Vieille‐Marchiset (ORCID: https://orcid.org/0000-0002-4382-8735)
- Patrícia R. Pitrez (ORCID: https://orcid.org/0000-0002-3116-0723)
- Francisca Correia
- Stéphanie Chanon (ORCID: https://orcid.org/0000-0001-6930-6671)
- David Laville (ORCID: https://orcid.org/0000-0002-0727-6195)
- Rui M Adão
- André Lourenço (ORCID: https://orcid.org/0000-0003-3650-5062)
- Liliana Moreira-Costa
- Frédéric Perros
- Marta Tavares-Silva
- Isabel Miranda
- Rui J. Cerqueira
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Universidad Complutense de Madrid (ES)
- Inserm (FR)
- Universidade do Porto (PT)
- Université Paris-Saclay (FR)
- Hospital de São João (PT)
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Hospices Civils de Lyon (FR)
- Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition (FR)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fcvm.2025.1736958
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia