Association between early arterial pH, base excess and lactate and 24-h mortality and neurological outcomes after cardiac arrest and cardiopulmonary resuscitation: a translational study
Arterial pH, base excess and lactate were early independent predictors of both 24-h mortality and neurological outcome following cardiac arrest in animal models and in humans. BE showed the highest predictive value for mortality, while lactate was the strongest predictor for poor neurological outcome.
Authors
- Marianna Cerrato (ORCID: https://orcid.org/0009-0007-6254-8337)
- Aurora Magliocca (ORCID: https://orcid.org/0000-0002-3908-3857)
- Elisa R. Zanier (ORCID: https://orcid.org/0000-0002-3011-8718)
- Francesca Callegari (ORCID: https://orcid.org/0000-0002-8381-7360)
- Ornella Tinelli
- Francesca Fumagalli
- Daria De Giorgio
- Giuseppe Ristagno
- Giulia Merigo
Institutions
- University of Milan (IT)
- Mario Negri Institute for Pharmacological Research (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1016/j.resplu.2026.101228
- Citations
- 1
- Primary Topic
- Renal function and acid-base balance
- Type
- article
- Field-Weighted Citation Impact
- 34.94