Cold agglutinin syndrome in a patient with metastatic breast cancer: a Case Report
This case illustrates a rare and severe immune complication of paclitaxel in metastatic breast cancer. The emergence of CAS not only limited systemic options but also reshaped the therapeutic trajectory, highlighting the need for close monitoring during cancer treatments. Early recognition, multidisciplinary approach, and prompt management can provide some improvement, although overall prognosis remains determined by the underlying malignancy.
Authors
- Beatriz Gosálbez
- Dina Rochate (ORCID: https://orcid.org/0000-0001-9965-7173)
- Sara Carvalhal (ORCID: https://orcid.org/0000-0002-6004-3286)
- Daniel Bandarra (ORCID: https://orcid.org/0000-0001-6128-1350)
- J. M. A. Ferreira
- Nidia Maltez Cunha
Institutions
- Algarve Biomedical Center (PT)
- University of Algarve (PT)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fmed.2025.1711809
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia