Real-world effectiveness of SGLT2 inhibitors in patients with HF and ESKD: a multicenter cohort study

SGLT2i are significantly associated with reduced 1 year all-cause hospitalization, mortality, and acute pulmonary edema in HF and ESKD patients. These findings highlight the potential therapeutic role of SGLT2i in this high-risk population, warranting further clinical trials to confirm their efficacy and safety.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-16
DOI
https://doi.org/10.3389/fcvm.2026.1652863
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Real-world effectiveness of SGLT2 inhibitors in patients with HF and ESKD: a multicenter cohort study

Kuan-Jui Tseng, Jheng-Yan Wu, Chia-Li Kao, Tsung Yu et al.
Frontiers in Cardiovascular Medicine
Diabetes Treatment and Management
article

Real-world effectiveness of SGLT2 inhibitors in patients with HF and ESKD: a multicenter cohort study

Kuan-Jui Tseng, Jheng-Yan Wu, Chia-Li Kao, Tsung Yu, Yu-Min Lin, Kuo-Chuan Hung
article en

Abstract

SGLT2i are significantly associated with reduced 1 year all-cause hospitalization, mortality, and acute pulmonary edema in HF and ESKD patients. These findings highlight the potential therapeutic role of SGLT2i in this high-risk population, warranting further clinical trials to confirm their efficacy and safety.

Frontiers in Cardiovascular MedicineVol. 13
E-Da Hospital (TW), Chi Mei Medical Center (TW), National Cheng Kung University (TW), I-Shou University (TW)
Good health and well-being
Openalex Percentile: Top 87%
Diabetes Treatment and Management
DOIOpen Access PDFOpenAlex
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Real-world effectiveness of SGLT2 inhibitors in patients with HF and ESKD: a multicenter cohort study — Kuan-Jui Tseng, Jheng-Yan Wu, et al. · Frontiers in Cardiovascular Medicine (2026) | TGRS Research Map | TGRS