WADD-SEPD Consensus on Psychological Treatment of Dual Disorders I: General Recommendations, Most Used Therapies, and Severe Mental Disorders

<b>Background/Objectives</b>: The treatment of dual disorders (DDs) must be comprehensive and multidisciplinary. There is evidence supporting the effectiveness of psychotherapy in their treatment. However, clinical guidelines, consensus statements, and reviews on the treatment of DDs typically devote considerably less space to psychological therapy than to pharmacological therapy. Therefore, this work aimed to synthesize the available evidence, recommendations, and clinical experience on the psychological treatment of DDs to reach a consensus. <b>Methods</b>: Two consensus methods were sequentially implemented: the nominal group technique and the Delphi method. <b>Results:</b> The first part of this consensus review encompassed a compilation of general recommendations for the psychological treatment of DDs, evidence on the efficacy of the most frequently used therapies, and recommendations for the psychological treatment of severe dual mental disorders. These disorders include schizophrenia and other psychotic disorders, bipolar disorders, depressive disorders, and obsessive compulsive disorders. <b>Conclusions</b>: (1) Psychological treatment is effective; (2) integrated psychological treatment is more effective; (3) motivational interviewing, cognitive behavioral therapy, and relapse prevention are the psychological interventions with the most supporting evidence; (4) the best alternative is multicomponent strategies; (5) the most frequently studied severe mental disorders are schizophrenia and depression; (6) for dual schizophrenia, motivational interviewing and integrated cognitive behavioral therapy combined with other components are recommended; (7) for dual depression, cognitive behavioral therapy with relapse prevention or motivational interviewing is recommended; (8) for dual bipolar disorder, group therapies with psychoeducation or relapse prevention and inclusion of the family, contingency management, and family intervention are recommended; (9) more empirical evidence is needed, especially for obsessive compulsive and schizoaffective disorders; and (10) more randomized clinical trials are needed to improve current methodological limitations.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-01-16
DOI
https://doi.org/10.3390/jcm15020730
Citations
1
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
33.12

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article

WADD-SEPD Consensus on Psychological Treatment of Dual Disorders I: General Recommendations, Most Used Therapies, and Severe Mental Disorders

A Benito, Judit Tirado-Muñoz, Ana Adan, Susana Jiménez-Murcia
1 citations
Journal of Clinical Medicine
Schizophrenia research and treatment
33.12
article

WADD-SEPD Consensus on Psychological Treatment of Dual Disorders I: General Recommendations, Most Used Therapies, and Severe Mental Disorders

A Benito, Judit Tirado-Muñoz, Ana Adan, Susana Jiménez-Murcia
article en
1 citations

Abstract

<b>Background/Objectives</b>: The treatment of dual disorders (DDs) must be comprehensive and multidisciplinary. There is evidence supporting the effectiveness of psychotherapy in their treatment. However, clinical guidelines, consensus statements, and reviews on the treatment of DDs typically devote considerably less space to psychological therapy than to pharmacological therapy. Therefore, this work aimed to synthesize the available evidence, recommendations, and clinical experience on the psychological treatment of DDs to reach a consensus. <b>Methods</b>: Two consensus methods were sequentially implemented: the nominal group technique and the Delphi method. <b>Results:</b> The first part of this consensus review encompassed a compilation of general recommendations for the psychological treatment of DDs, evidence on the efficacy of the most frequently used therapies, and recommendations for the psychological treatment of severe dual mental disorders. These disorders include schizophrenia and other psychotic disorders, bipolar disorders, depressive disorders, and obsessive compulsive disorders. <b>Conclusions</b>: (1) Psychological treatment is effective; (2) integrated psychological treatment is more effective; (3) motivational interviewing, cognitive behavioral therapy, and relapse prevention are the psychological interventions with the most supporting evidence; (4) the best alternative is multicomponent strategies; (5) the most frequently studied severe mental disorders are schizophrenia and depression; (6) for dual schizophrenia, motivational interviewing and integrated cognitive behavioral therapy combined with other components are recommended; (7) for dual depression, cognitive behavioral therapy with relapse prevention or motivational interviewing is recommended; (8) for dual bipolar disorder, group therapies with psychoeducation or relapse prevention and inclusion of the family, contingency management, and family intervention are recommended; (9) more empirical evidence is needed, especially for obsessive compulsive and schizoaffective disorders; and (10) more randomized clinical trials are needed to improve current methodological limitations.

Journal of Clinical MedicineVol. 15(2)
Universidad Cardenal Herrera CEU (ES), Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition (ES), Bellvitge University Hospital (ES), IMDEA Networks (ES), Institut d'Investigació Biomédica de Bellvitge (ES), Sociedad Española de Medicina de Familia y Comunitaria (ES), Hospital General Universitario De Valencia (ES), Spanish Society of Hematology and Hemotherapy (ES), MSD (Spain) (ES), Universitat de Barcelona (ES), Universidad Europea de Madrid (ES)
Centres de Recerca de Catalunya, Generalitat de Catalunya, Ministerio de Ciencia e Innovación, Instituto de Salud Carlos III, European Regional Development Fund, Agencia Estatal de Investigación
Reduced inequalities
Openalex Percentile: Top 2%
Schizophrenia research and treatment
33.12
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