Does early pregnancy exposure to macrolide antibiotics lead to major birth defects? A systematic review and meta-analysis
Existing evidence suggests that early pregnancy use of macrolide antibiotics does not increase the risk of major birth defects. In clinical practice, healthcare providers and pregnant women can use these antibiotics cautiously based on the specific infection situation.
Authors
- Hong Su (ORCID: https://orcid.org/0000-0002-4673-6449)
- Xiao Huang (ORCID: https://orcid.org/0000-0002-7536-1762)
- Yanbin Yang
- Ying Song
- Yu Sun
- Jing Zhang (ORCID: https://orcid.org/0000-0001-6619-2592)
- Quanhong Li
Institutions
- Kunming Children's Hospital (CN)
- Yunnan Maternal and Child Health (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2026-01-16
- DOI
- https://doi.org/10.3389/fpubh.2026.1513736
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00