From Functional Disorder to a Life-Threatening Emergency: A Rare Adolescent Case of Thyrotoxicosis

Thyroid storm is a rare but life-threatening endocrine emergency that requires rapid recognition and multidisciplinary care. We report the case of a 16-year-old female patient admitted to the emergency department with acute confusion, fever, and tachycardia, in whom severe thyrotoxicosis was confirmed. Her Burch-Wartofsky score was 40, consistent with an impending thyroid storm. Graves' disease had been previously diagnosed, but treatment was delayed, and influenza B infection acted as a precipitating factor. Management with antithyroid drugs, beta-blockers, and intensive care led to clinical improvement, with thyroidectomy subsequently planned. This case highlights the importance of early diagnosis, coordinated management, and awareness of infection as a trigger, while emphasizing the limitations of antithyroid therapy in adolescents.

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Publication Details

Journal
Cureus
Published
2026-01-15
DOI
https://doi.org/10.7759/cureus.101630
Primary Topic
Thyroid Disorders and Treatments
Type
article
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0.00
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article

From Functional Disorder to a Life-Threatening Emergency: A Rare Adolescent Case of Thyrotoxicosis

Gauthier Leclercq, Laurent Pâques, Emma Carles, Hugo Picardo et al.
Cureus
Thyroid Disorders and Treatments
article

From Functional Disorder to a Life-Threatening Emergency: A Rare Adolescent Case of Thyrotoxicosis

Gauthier Leclercq, Laurent Pâques, Emma Carles, Hugo Picardo, Fabien Guerisse, Séphora Chanhoun
article en

Abstract

Thyroid storm is a rare but life-threatening endocrine emergency that requires rapid recognition and multidisciplinary care. We report the case of a 16-year-old female patient admitted to the emergency department with acute confusion, fever, and tachycardia, in whom severe thyrotoxicosis was confirmed. Her Burch-Wartofsky score was 40, consistent with an impending thyroid storm. Graves' disease had been previously diagnosed, but treatment was delayed, and influenza B infection acted as a precipitating factor. Management with antithyroid drugs, beta-blockers, and intensive care led to clinical improvement, with thyroidectomy subsequently planned. This case highlights the importance of early diagnosis, coordinated management, and awareness of infection as a trigger, while emphasizing the limitations of antithyroid therapy in adolescents.

CureusVol. 18(1)
University of Mons (BE), Grand Charleroi Hospital (BE)
Good health and well-being
Openalex Percentile: Top 87%
Thyroid Disorders and Treatments
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From Functional Disorder to a Life-Threatening Emergency: A Rare Adolescent Case of Thyrotoxicosis — Gauthier Leclercq, Laurent Pâques, et al. · Cureus (2026) | TGRS Research Map | TGRS