Silver-Containing Collagen–Chitosan Materials Promising for Medical Applications: Synthesis and Structure

New collagen–chitosan materials containing Ag nanoparticles, promising for the design of wound dressings, were synthesized from a porous hybrid material derived from collagen and chitosan in the powder and gel forms. An original process concept for the formation of hybrid biomaterials is presented. The materials were synthesized using powders of collagen and chitosan polymers pre-modified with Ag nanoparticles obtained by metal vapor synthesis. The metal-containing powder systems were used as precursors for the preparation of gels, which were freeze-dried to give porous hybrid materials. Nanocomposites were studied using XPS, PXRD, and SEM/EDX methods. Homogeneous distribution of Ag nanoparticles over the collagen–chitosan composite bulk was found, and the composition and electronic state of the metal in the material was examined.

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Publication Details

Journal
Russian Journal of Inorganic Chemistry
Published
2025-10-01
DOI
https://doi.org/10.1134/s0036023625603009
Primary Topic
Collagen: Extraction and Characterization
Type
article
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article

Silver-Containing Collagen–Chitosan Materials Promising for Medical Applications: Synthesis and Structure

N. S. Melekhina, A. S. Golub, P. R. Voloshina, K. M. Borisov et al.
Russian Journal of Inorganic Chemistry
Collagen: Extraction and Characterization
article

Silver-Containing Collagen–Chitosan Materials Promising for Medical Applications: Synthesis and Structure

N. S. Melekhina, A. S. Golub, P. R. Voloshina, K. M. Borisov, A. Yu. Pereyaslavtsev, A. Yu. Vasil’kov
article en

Abstract

New collagen–chitosan materials containing Ag nanoparticles, promising for the design of wound dressings, were synthesized from a porous hybrid material derived from collagen and chitosan in the powder and gel forms. An original process concept for the formation of hybrid biomaterials is presented. The materials were synthesized using powders of collagen and chitosan polymers pre-modified with Ag nanoparticles obtained by metal vapor synthesis. The metal-containing powder systems were used as precursors for the preparation of gels, which were freeze-dried to give porous hybrid materials. Nanocomposites were studied using XPS, PXRD, and SEM/EDX methods. Homogeneous distribution of Ag nanoparticles over the collagen–chitosan composite bulk was found, and the composition and electronic state of the metal in the material was examined.

Russian Journal of Inorganic ChemistryVol. 70(10)
A. N. Nesmeyanov Institute of Organoelement Compounds (RU), All Russia Research Institute of Automatics (RU), Institute of Synthetic Polymeric Materials (RU)
Openalex Percentile: Top 41%
Collagen: Extraction and Characterization
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