Identification of empagliflozin-related hub genes in atherosclerosis and their correlations with immune infiltration: Network pharmacology and bioinformatics analyses
Our network pharmacology and bioinformatics analyses provide a comprehensive understanding of the potential mechanisms of empagliflozin in AS at the genomic level, with the discovery of significant correlations between the screened hub genes and various immune cell subsets.
Authors
- Xinyu Liu
- Liming Chen
- Yicheng Rong
- Le Yang
- Yuanyuan Sun
Institutions
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1371/journal.pone.0339956
- Citations
- 1
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 24.43