Genetic subtypes associated with multiple sclerosis severity and response to treatment
Genetic clustering reveals clinically meaningful MS subtypes with distinct prognoses and treatment responses, highlighting its potential role in precision medicine for MS management.
Authors
- Emma Tallantyre (ORCID: https://orcid.org/0000-0002-3760-6634)
- Ray Wynford‐Thomas
- Michael Andrew Lawton (ORCID: https://orcid.org/0000-0002-3419-0354)
- Katharine Harding (ORCID: https://orcid.org/0000-0001-6299-5582)
- Nienke Mekkes (ORCID: https://orcid.org/0000-0002-5454-0235)
- Inge R. Holtman (ORCID: https://orcid.org/0000-0001-9752-4756)
- Mark Wardle (ORCID: https://orcid.org/0000-0002-4543-7068)
- Dr Neil Robertson
- Sam Loveless
- Karim L Kreft
- Emeka Uzochukwu
- J William L Brown
Institutions
- University Medical Center Groningen (NL)
- University of Nottingham (GB)
- University of Groningen (NL)
- University of Cambridge (GB)
- Royal Gwent Hospital (GB)
- University Hospital of Wales (GB)
- University of Bristol (GB)
- Institute of Mental Health (GB)
- University of Wales Institute Cardiff (SG)
- Cardiff University (GB)
- Cardiff Metropolitan University (GB)
- University of Wales (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2026-01-16
- DOI
- https://doi.org/10.1136/jnnp-2025-337337
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00