Extrahepatic Autoimmune Diseases in Autoimmune Hepatitis: Their Prevalence, Predictors, and Influence on Early Treatment Outcomes

In the Han Chinese population, 23.98% of AIH patients had EADs, with Sjogren's syndrome and autoimmune thyroid disease being the most common. ANA positivity was a significant risk factor for EADs. EAD patients had a poorer initial treatment response at three months, but comparable long-term biochemical response from six months.

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Publication Details

Journal
Journal of Clinical and Translational Hepatology
Published
2026-01-15
DOI
https://doi.org/10.14218/jcth.2025.00424
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
0.00

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article

Extrahepatic Autoimmune Diseases in Autoimmune Hepatitis: Their Prevalence, Predictors, and Influence on Early Treatment Outcomes

Caimei Yuan, Ying Ma, Weihao Zhao, Jia-Nan Cui et al.
Journal of Clinical and Translational Hepatology
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Extrahepatic Autoimmune Diseases in Autoimmune Hepatitis: Their Prevalence, Predictors, and Influence on Early Treatment Outcomes

Caimei Yuan, Ying Ma, Weihao Zhao, Jia-Nan Cui, Kevin Ou, Qing-Fang Xiong, Yong-Feng Yang, Bin Liu
article en

Abstract

In the Han Chinese population, 23.98% of AIH patients had EADs, with Sjogren's syndrome and autoimmune thyroid disease being the most common. ANA positivity was a significant risk factor for EADs. EAD patients had a poorer initial treatment response at three months, but comparable long-term biochemical response from six months.

Journal of Clinical and Translational HepatologyVol. 000(000)
Nanjing University of Chinese Medicine (CN), Nanjing Municipal Center for Disease Control And Prevention (CN)
Government of Jiangsu Province, Nanjing University of Chinese Medicine, Nanjing University
No poverty
Openalex Percentile: Top 86%
Liver Diseases and Immunity
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