4-week aerobic exercise training regulates systemic macrophage polarization in obese mice
Short-term aerobic exercise is sufficient to promote M2 macrophage polarization and dampen systemic inflammation in obese mice. These findings underline the rapid immunomodulatory potential of exercise and support its role as an effective non-pharmacological approach to counteract obesity-related inflammation and metabolic dysfunction.
Authors
- Jeong-Sun Ju (ORCID: https://orcid.org/0000-0001-7276-9941)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-9366-1208)
- Haibin Zhang (ORCID: https://orcid.org/0000-0003-0366-4040)
- JingAo Qin
- Xin Zhang
- XinPeng Gao
Institutions
- University of Suwon (KR)
- Suwon Science College (KR)
- Yulin University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2026-01-15
- DOI
- https://doi.org/10.7717/peerj.20604
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00