Runx2 acetylation enhances pulmonary inflammation in chronic obstructive pulmonary disease through activating CDK8
These results indicated that Sirt3 depletion-induced Runx2 acetylation contributes to CDK8 activation and pulmonary inflammation in the progression of COPD.
Authors
- Dong-Xu Hua (ORCID: https://orcid.org/0009-0008-9919-2888)
- Hongyun Zhao (ORCID: https://orcid.org/0000-0002-1251-3888)
- Yicheng Ma (ORCID: https://orcid.org/0000-0001-9569-3169)
- Danlei Chen (ORCID: https://orcid.org/0000-0003-4903-1222)
- Qi-Yuan He (ORCID: https://orcid.org/0009-0004-2181-6882)
- Ping Wang (ORCID: https://orcid.org/0000-0001-6474-2722)
- Ju-Hong Wu
- Jun Fei (ORCID: https://orcid.org/0000-0002-0504-4534)
- Lin Fu
- Min-Min Tang
- Tian-Rui Sui
- Fei Tang
- Zhi-Yong Wu
- Wei Cao
- Jing Yang
Institutions
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Xi'an Chest Hospital (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1186/s12931-025-03475-4
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00