Comparative analysis of patient-derived organoids among oral squamous cell carcinoma and mucosa identifies the distinct features

Our comparative analysis delineates distinct features between PDO-T and PDO-N in morphology, biomarker expression, and drug response. These findings provide an intuitive framework for their identification, thereby improving the accuracy of drug screening and enhancing the translational value of PDOs.

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Publication Details

Journal
Archives of Oral Biology
Published
2026-01-15
DOI
https://doi.org/10.1016/j.archoralbio.2026.106520
Citations
1
Primary Topic
Cancer Cells and Metastasis
Type
article
Field-Weighted Citation Impact
24.20
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article

Comparative analysis of patient-derived organoids among oral squamous cell carcinoma and mucosa identifies the distinct features

Xiaodong Feng, Jianguo GAN, Guiquan Zhu, Dan Yang
1 citations
Archives of Oral Biology
Cancer Cells and Metastasis
24.20
article

Comparative analysis of patient-derived organoids among oral squamous cell carcinoma and mucosa identifies the distinct features

Xiaodong Feng, Jianguo GAN, Guiquan Zhu, Dan Yang
article en
1 citations

Abstract

Our comparative analysis delineates distinct features between PDO-T and PDO-N in morphology, biomarker expression, and drug response. These findings provide an intuitive framework for their identification, thereby improving the accuracy of drug screening and enhancing the translational value of PDOs.

Archives of Oral BiologyVol. 184
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Sichuan University (CN), National Clinical Research (US), State Key Laboratory of Oral Diseases
Good health and well-being
Openalex Percentile: Top 2%
Cancer Cells and Metastasis
24.20
DOIOpen Access PDFOpenAlex
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Comparative analysis of patient-derived organoids among oral squamous cell carcinoma and mucosa identifies the distinct features — Xiaodong Feng, Jianguo GAN, et al. · Archives of Oral Biology (2026) | TGRS Research Map | TGRS