Interventions to Prevent Postinflammatory Hyperpigmentation After Laser and Energy‐Based Device Treatments: A Systematic Review and Network Meta‐Analysis
This systematic review and NMA indicate that topical corticosteroids and intradermal TXA may offer greater protection against laser-induced PIH than sunscreen monotherapy. Preventive strategies should be incorporated into laser treatment planning, particularly for patients with higher risk of hyperpigmentation. Overall, the findings support an evidence-based and individualized approach to PIH prevention. Interpretation should remain cautious due to the limited number and modest sample sizes of included trials.
Authors
- Sukrit Kanchanasurakit (ORCID: https://orcid.org/0000-0002-1268-2665)
- Sasitorn Yenyuwadee (ORCID: https://orcid.org/0000-0002-5685-8271)
- Surasak Saokaew (ORCID: https://orcid.org/0000-0002-1382-0660)
- J. Li
- Supisara Wongdama (ORCID: https://orcid.org/0000-0002-3818-6889)
- Woraphong Manuskiatti (ORCID: https://orcid.org/0000-0001-8393-7963)
Institutions
- Siriraj Hospital (TH)
- Chulalongkorn University (TH)
- Mahidol University (TH)
- Vajira Hospital (TH)
- University of Phayao (TH)
Publication Details
- Journal
- Lasers in Surgery and Medicine
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1002/lsm.70098
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00