Biochemical failure after radical prostatectomy with PSA ≤ 1 ng/mL: prediction of PSMA-positive metastatic disease
ISUP grade > 3, time to BCR ≤ 26 months, pN1 status, and persistent disease after surgery indicated a higher likelihood of PSMA-positive metastatic disease in a homogeneous cohort of patients with biochemical failure and low PSA values. pN1 status and persistent disease were significant predictors of metastatic disease also in patients with PSA levels < 0.5 ng/mL.
Authors
- Helena Rosarno
- Antonino Restuccia
- Francesco Cicone (ORCID: https://orcid.org/0000-0003-4664-1965)
- Giuseppe Lucio Cascini (ORCID: https://orcid.org/0000-0003-0332-2606)
- Giulia Santo
Institutions
- University of Molise (IT)
- Magna Graecia University (IT)
- Azienda Ospedaliero-Universitaria "Renato Dulbecco" (IT)
- Azienda Ospedaliera Pugliese Ciaccio (IT)
Publication Details
- Journal
- Annals of Nuclear Medicine
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1007/s12149-026-02153-9
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission