Alterations in N6-Methyladenosine (m <sup>6</sup> A) Modification of mRNA in the Sclera of Form-Deprived Myopic Guinea Pig
This study highlights the role of m<sup>6</sup>A methylation, mediated by METTL14, in the regulating of key genes involved in calcium signaling and ECM remodeling during myopia progression. These findings suggest that targeting m<sup>6</sup>A modifications may could offer new therapeutic strategies for the treatment of myopia.
Authors
- Junxiong Wang (ORCID: https://orcid.org/0000-0001-6998-0711)
- Jiantao Ren
- Rong Luan
- Lamberg Ba
- Kai Wen (ORCID: https://orcid.org/0009-0008-2464-6486)
- Jing Sun
- Shuaixin Lu
Institutions
- Tianjin Medical University Eye Hospital (CN)
- He Eye Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Current Eye Research
- Published
- 2026-01-14
- DOI
- https://doi.org/10.1080/02713683.2026.2613441
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00