Polygenic Risk, Trait Variables, and External Stressors in Fatal and Nonfatal Suicidal Behavior
This case-control study found that genetic liability for suicide attempt was associated with clinical characteristics, internal traits, and external stressors, highlighting the complexity of genetic and environmental interactions. Larger studies with detailed phenotyping are needed to clarify genetic-environment contributions to suicide risk.
Authors
- M. Kim
- Hanga Galfalvy (ORCID: https://orcid.org/0000-0001-7156-6106)
- J. John Mann
Institutions
- New York Psychoanalytic Society and Institute (US)
- New York Genome Center (US)
- New York State Psychiatric Institute
- Columbia University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.54325
- Primary Topic
- Suicide and Self-Harm Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00