The association of antihistamines and new-onset osteoarthritis in patients with autoimmune disease: a population-based cohort study

In this population-based cohort study, we found that antihistamine use was associated with a significantly increased risk of osteoarthritis in patients with autoimmune disease. Further efforts are needed to minimize the potential population drawbacks of these therapies in high-risk groups.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-15
DOI
https://doi.org/10.3389/fimmu.2025.1712222
Citations
1
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
46.80

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article

The association of antihistamines and new-onset osteoarthritis in patients with autoimmune disease: a population-based cohort study

T. Y. Chao, Pei-Lun Liao, Tsung-Yuan Yang, Chih-Jung Yeh et al.
1 citations
Frontiers in Immunology
Osteoarthritis Treatment and Mechanisms
46.80
article

The association of antihistamines and new-onset osteoarthritis in patients with autoimmune disease: a population-based cohort study

T. Y. Chao, Pei-Lun Liao, Tsung-Yuan Yang, Chih-Jung Yeh, Gwo-Ping Jong, Chih-Feng Chang
article en
1 citations

Abstract

In this population-based cohort study, we found that antihistamine use was associated with a significantly increased risk of osteoarthritis in patients with autoimmune disease. Further efforts are needed to minimize the potential population drawbacks of these therapies in high-risk groups.

Frontiers in ImmunologyVol. 16
Chung Shan Medical University Hospital (TW), Taichung Armed Forces General Hospital (TW), National Defense Medical Center (TW), Chung Shan Medical University (TW)
Chung Shan Medical University, Chung Shan Medical University Hospital
Good health and well-being
Openalex Percentile: Top 1%
Osteoarthritis Treatment and Mechanisms
46.80
DOIOpen Access PDFOpenAlex
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