In Silico Investigation Reveals IL-6 as a Key Target of Asiatic Acid in Osteoporosis: Insights from Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
This integrative in silico study provides mechanistic insight into the potential anti-osteoporotic actions of asiatic acid, implicating <i>IL-6</i> as a plausible upstream molecular target. These results establish a robust mechanistic framework for future translational studies exploring asiatic acid as a natural therapeutic candidate for osteoporosis.
Authors
- Wanatsanan Chulrik (ORCID: https://orcid.org/0000-0003-2804-4921)
- Aman Tedasen (ORCID: https://orcid.org/0000-0002-1350-1424)
- Nateelak Kooltheat (ORCID: https://orcid.org/0000-0001-7623-854X)
- Thitinat Duangchan (ORCID: https://orcid.org/0000-0002-7404-6664)
- Rungruedee Kimseng (ORCID: https://orcid.org/0000-0002-2580-9477)
Institutions
- University of Kentucky (US)
- Walailak University (TH)
Publication Details
- Journal
- Medical Sciences
- Published
- 2026-01-15
- DOI
- https://doi.org/10.3390/medsci14010041
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Walailak University