Case Report: FIA plus venetoclax in a patient on hemodialysis

The safe and effective delivery of curative cytotoxic chemotherapy for acute myeloid leukemia (AML) in patients receiving intermittent hemodialysis (IHD) for end-stage renal disease (ESRD) remains a clinical challenge; pharmacological and logistical barriers necessitate close interdisciplinary coordination. In this case, we report a 65-year-old female patient with chronic ESRD on IHD and newly diagnosed AML who achieved complete remission (CR) after treatment with fludarabine, idarubicin, and cytarabine plus venetoclax (i.e., FIA + venetoclax).

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-15
DOI
https://doi.org/10.3389/fonc.2025.1740357
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

Case Report: FIA plus venetoclax in a patient on hemodialysis

Kayleigh Marx, Musa Yılmaz, T. M. Kadia, Nicholas J. Short et al.
Frontiers in Oncology
Acute Myeloid Leukemia Research
article

Case Report: FIA plus venetoclax in a patient on hemodialysis

Kayleigh Marx, Musa Yılmaz, T. M. Kadia, Nicholas J. Short, Courtney D. DiNardo, Wei Ying Jen, Farhad Ravandi, Naval G. Daver, Jacob E. Herstein, Ghayas C. Issa, J. Michael Savoy
article en

Abstract

The safe and effective delivery of curative cytotoxic chemotherapy for acute myeloid leukemia (AML) in patients receiving intermittent hemodialysis (IHD) for end-stage renal disease (ESRD) remains a clinical challenge; pharmacological and logistical barriers necessitate close interdisciplinary coordination. In this case, we report a 65-year-old female patient with chronic ESRD on IHD and newly diagnosed AML who achieved complete remission (CR) after treatment with fludarabine, idarubicin, and cytarabine plus venetoclax (i.e., FIA + venetoclax).

Frontiers in OncologyVol. 15
The University of Texas MD Anderson Cancer Center (US), The University of Texas Health Science Center at Houston (US)
Good health and well-being
Openalex Percentile: Top 89%
Acute Myeloid Leukemia Research
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