Lipid Dependence of CYP3A4 Activity in Nanodiscs
CYP3A4 is the main xenobiotic metabolizing enzyme in the human body, as it is in volved in metabolism of ~30% of drugs on the market as well as of many other compounds, from small molecules such as ethanol to large drugs such as erythromycin and cyclosporine [...].
Authors
- Yelena V. Grinkova (ORCID: https://orcid.org/0000-0003-2902-9440)
- Ilia G. Denisov (ORCID: https://orcid.org/0000-0002-7878-2626)
- Stephen G. Sligar
Institutions
- University of Illinois Urbana-Champaign (US)
- Urbana University (US)
- Goodwin College (US)
Publication Details
- Journal
- Biology
- Published
- 2026-01-15
- DOI
- https://doi.org/10.3390/biology15020156
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health