Development of an Electrophoresis Machine for Rapid Genotype Analysis

The diverse use of electrophoretic technologies is frequent for both chemical and biological processes having a significant in learning and interaction with biological binding patterns, such as specification, physicochemical characteristics, redox states, and ligand exchange. The advancements in the modeling of electrophoresis systems with the capacity to simultaneously evaluate three samples, with a smart alarming system to indicate a complete procedure would be fabricated. Due to the two-way nature of the fluid-structure interaction, the deformation of the particles is with a sizable impact on the flow field surrounding them. Up until now, only electrophoresis of either hard particles or soft particles without cores has addressed the challenge of a rapid test for genotype. The developed device comprises of 1.5KW transformer, a regulator, a timer relay, and an alarm system. The produced device is capable of evaluating the genotype in humans by using blood as a sample under electric current within a few minutes. The device contains three tank outputs instead of the conventional two tanks with a capacity to evaluate three samples simultaneously, embedded in the control is a mechanism for monitoring and visualization genotyping. The developed device allows for multiple gels to be stacked in the tank, whereby it can analyze 30-60 samples. The developed Electrophoresis device allows analysis of size and charge, parameters inaccessible to liquid-phase methods: thus, genotyping size patterns, variable length repeats, and haplotypes are possible, as well as adaptability to typing of point variations using protocols that createa difference detectable by the electrophoresis device.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-15
DOI
https://doi.org/10.5281/zenodo.18256070
Primary Topic
Microfluidic and Capillary Electrophoresis Applications
Type
article
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article

Development of an Electrophoresis Machine for Rapid Genotype Analysis

Idowu Adetona Ayoade, Olusola Akinde, Abdulhafeez Olaide Ayoade
Zenodo (CERN European Organization for Nuclear Research)
Microfluidic and Capillary Electrophoresis Applications
article

Development of an Electrophoresis Machine for Rapid Genotype Analysis

Idowu Adetona Ayoade, Olusola Akinde, Abdulhafeez Olaide Ayoade
article en

Abstract

The diverse use of electrophoretic technologies is frequent for both chemical and biological processes having a significant in learning and interaction with biological binding patterns, such as specification, physicochemical characteristics, redox states, and ligand exchange. The advancements in the modeling of electrophoresis systems with the capacity to simultaneously evaluate three samples, with a smart alarming system to indicate a complete procedure would be fabricated. Due to the two-way nature of the fluid-structure interaction, the deformation of the particles is with a sizable impact on the flow field surrounding them. Up until now, only electrophoresis of either hard particles or soft particles without cores has addressed the challenge of a rapid test for genotype. The developed device comprises of 1.5KW transformer, a regulator, a timer relay, and an alarm system. The produced device is capable of evaluating the genotype in humans by using blood as a sample under electric current within a few minutes. The device contains three tank outputs instead of the conventional two tanks with a capacity to evaluate three samples simultaneously, embedded in the control is a mechanism for monitoring and visualization genotyping. The developed device allows for multiple gels to be stacked in the tank, whereby it can analyze 30-60 samples. The developed Electrophoresis device allows analysis of size and charge, parameters inaccessible to liquid-phase methods: thus, genotyping size patterns, variable length repeats, and haplotypes are possible, as well as adaptability to typing of point variations using protocols that createa difference detectable by the electrophoresis device.

Zenodo (CERN European Organization for Nuclear Research)
Abiola Ajimobi Technical University Ibadan (NG)
Openalex Percentile: Top 87%
Microfluidic and Capillary Electrophoresis Applications
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Development of an Electrophoresis Machine for Rapid Genotype Analysis — Idowu Adetona Ayoade, Olusola Akinde, et al. · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS