Expert Opinion and Evidence-Based Review on Maintenance Therapy Step-Down in Patients With Severe Asthma Controlled With Biologics

Expert perspectives, together with clinical trial and real-world evidence, support a gradual, individualized approach guided by objective markers and close monitoring. The algorithm proposed will provide clinicians with a structured, evidence-informed framework to guide the safe and effective reduction of SA maintenance therapy in real-world practice.

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Publication Details

Journal
Open Respiratory Archives
Published
2026-01-15
DOI
https://doi.org/10.1016/j.opresp.2026.100577
Primary Topic
Asthma and respiratory diseases
Type
article
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article

Expert Opinion and Evidence-Based Review on Maintenance Therapy Step-Down in Patients With Severe Asthma Controlled With Biologics

Pilar Cebollero, Gregorio Soto Campos, Santiago Quirce, Eva Martínez Moragón et al.
Open Respiratory Archives
Asthma and respiratory diseases
article

Expert Opinion and Evidence-Based Review on Maintenance Therapy Step-Down in Patients With Severe Asthma Controlled With Biologics

Pilar Cebollero, Gregorio Soto Campos, Santiago Quirce, Eva Martínez Moragón, Juan Carlos Miralles López, Carlos Almonacid, Pilar Ausín, Mar Mosteiro, Alicia Padilla Galo, Fernando Rodríguez, Vicente Plaza
article en

Abstract

Expert perspectives, together with clinical trial and real-world evidence, support a gradual, individualized approach guided by objective markers and close monitoring. The algorithm proposed will provide clinicians with a structured, evidence-informed framework to guide the safe and effective reduction of SA maintenance therapy in real-world practice.

Open Respiratory ArchivesVol. 8(2)
Universitat Pompeu Fabra (ES), Hospital Universitario La Paz (ES), Hospital de Sant Pau (ES), University Hospital Complex Of Vigo (ES), Hospital Universitario Puerta de Hierro Majadahonda (ES), Instituto de Investigación Marqués de Valdecilla (ES), Hospital Universitario Doctor Peset (ES), Hospital Reina Sofía de Murcia (ES), Hospital Jerez Puerta del Sur (ES), Hospital Clínico Universitario Virgen de la Victoria (ES)
Good health and well-being
Openalex Percentile: Top 88%
Asthma and respiratory diseases
DOIOpen Access PDFOpenAlex
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Expert Opinion and Evidence-Based Review on Maintenance Therapy Step-Down in Patients With Severe Asthma Controlled With Biologics — Pilar Cebollero, Gregorio Soto Campos, et al. · Open Respiratory Archives (2026) | TGRS Research Map | TGRS