Synchronous Primary Gallbladder Cancer and Ipsilateral Renal Cell Carcinoma: A Case Report

The synchronous occurrence of primary gallbladder carcinoma and ipsilateral renal cell carcinoma is exceptionally rare. Such presentations pose significant diagnostic challenges, particularly in differentiating synchronous primary tumors from metastatic disease. We report the case of a 57-year-old male patient who presented to the clinic in October 2025 with right upper quadrant abdominal pain and was found to have both gallbladder carcinoma and a right renal mass. Comprehensive imaging confirmed two distinct primary malignancies. The patient underwent laparoscopic radical cholecystectomy combined with radical right nephrectomy. A pathological analysis was performed, which showed that the process was gallbladder cancer and renal cell carcinoma. The patient is now under follow-up. This report highlights the importance of accurate diagnosis and multidisciplinary management of rare synchronous malignancies.

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Journal
Cureus
Published
2026-01-15
DOI
https://doi.org/10.7759/cureus.101579
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
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article

Synchronous Primary Gallbladder Cancer and Ipsilateral Renal Cell Carcinoma: A Case Report

Salwan K Alobaidi
Cureus
Multiple and Secondary Primary Cancers
article

Synchronous Primary Gallbladder Cancer and Ipsilateral Renal Cell Carcinoma: A Case Report

Salwan K Alobaidi
article en

Abstract

The synchronous occurrence of primary gallbladder carcinoma and ipsilateral renal cell carcinoma is exceptionally rare. Such presentations pose significant diagnostic challenges, particularly in differentiating synchronous primary tumors from metastatic disease. We report the case of a 57-year-old male patient who presented to the clinic in October 2025 with right upper quadrant abdominal pain and was found to have both gallbladder carcinoma and a right renal mass. Comprehensive imaging confirmed two distinct primary malignancies. The patient underwent laparoscopic radical cholecystectomy combined with radical right nephrectomy. A pathological analysis was performed, which showed that the process was gallbladder cancer and renal cell carcinoma. The patient is now under follow-up. This report highlights the importance of accurate diagnosis and multidisciplinary management of rare synchronous malignancies.

CureusVol. 18(1)
American Society for Gastrointestinal Endoscopy (US)
Good health and well-being
Openalex Percentile: Top 87%
Multiple and Secondary Primary Cancers
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Synchronous Primary Gallbladder Cancer and Ipsilateral Renal Cell Carcinoma: A Case Report — Salwan K Alobaidi · Cureus (2026) | TGRS Research Map | TGRS