Unveiling cholesterol metabolism-related gene ACOX2: a multi-omics discovery of a novel biomarker in IgA nephropathy
This study uncovers a cholesterol metabolism-related regulatory axis in IgAN, establishes ACOX2 as a protective biomarker, and highlights a therapeutically actionable pathway; it provides mechanistic insights and translational opportunities for biomarker development and drug discovery.
Authors
- Xiaoqi Deng
- Lin Mei (ORCID: https://orcid.org/0000-0001-5772-1229)
- Yun Lin (ORCID: https://orcid.org/0009-0006-8683-8622)
- Li Ma
- Yu Luo
- Jinlan Wu
- Mengxi He
Institutions
- Zigong First People's Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2026-01-15
- DOI
- https://doi.org/10.1186/s41065-026-00639-0
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00