Magnesium Toxicity in an Obstetric Patient Due to Preeclampsia-Related Renal Dysfunction Despite Administration of a Standard Pritchard Regimen: A Case Report

Magnesium toxicity could occur in the treatment of preeclampsia/eclampsia, especially when the patient has coexisting renal impairment. If undetected and promptly treated, hypermagnesemia can cause severe fetomaternal complications and death. We present the case of a 22-year-old pregnant woman at 32 weeks of gestation, who was referred to our hospital with eclampsia, treated with intramuscular magnesium sulfate following a standard Pritchard regimen. An emergency cesarean section was carried out under general anesthesia due to multiorgan dysfunction. Following the cesarean delivery, she was successfully managed with mechanical ventilation and hemodialysis.

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Journal
Cureus
Published
2026-01-15
DOI
https://doi.org/10.7759/cureus.101584
Primary Topic
Pregnancy and preeclampsia studies
Type
article
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article

Magnesium Toxicity in an Obstetric Patient Due to Preeclampsia-Related Renal Dysfunction Despite Administration of a Standard Pritchard Regimen: A Case Report

Ambrose Rukewe, Onochie U Nweze, Ndapewoshali L Pinehas
Cureus
Pregnancy and preeclampsia studies
article

Magnesium Toxicity in an Obstetric Patient Due to Preeclampsia-Related Renal Dysfunction Despite Administration of a Standard Pritchard Regimen: A Case Report

Ambrose Rukewe, Onochie U Nweze, Ndapewoshali L Pinehas
article en

Abstract

Magnesium toxicity could occur in the treatment of preeclampsia/eclampsia, especially when the patient has coexisting renal impairment. If undetected and promptly treated, hypermagnesemia can cause severe fetomaternal complications and death. We present the case of a 22-year-old pregnant woman at 32 weeks of gestation, who was referred to our hospital with eclampsia, treated with intramuscular magnesium sulfate following a standard Pritchard regimen. An emergency cesarean section was carried out under general anesthesia due to multiorgan dysfunction. Following the cesarean delivery, she was successfully managed with mechanical ventilation and hemodialysis.

CureusVol. 18(1)
University of Namibia (NA), National Art Gallery of Namibia (NA)
Good health and well-being
Openalex Percentile: Top 88%
Pregnancy and preeclampsia studies
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