Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study
Claims data from a national healthcare insurance fund in the Netherlands showed that only 1.7% of patients with post-stroke spasticity received botulinum toxin-A. Botulinum toxin-A treatment doses and intervals varied widely across patients and most patients received only 1 or 2 botulinum toxin-A injection cycles. Our results suggest undertreatment of spasticity with botulinum toxin-A and suboptimal treatment adherence in Dutch clinical practice.
Authors
- Thom S. Lysen (ORCID: https://orcid.org/0000-0002-7593-935X)
- Hanne van Ballegooijen
- Max van Wijk (ORCID: https://orcid.org/0000-0003-4647-9806)
- Alexander C.H. Geurts
- Mary Verhoeven
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- IQVIA (United Kingdom) (GB)
- IQVIA (United States) (US)
- Ipsen (Netherlands) (NL)
Publication Details
- Journal
- Journal of Rehabilitation Medicine
- Published
- 2026-01-15
- DOI
- https://doi.org/10.2340/jrm.v58.43952
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ipsen