Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study

Claims data from a national healthcare insurance fund in the Netherlands showed that only 1.7% of patients with post-stroke spasticity received botulinum toxin-A. Botulinum toxin-A treatment doses and intervals varied widely across patients and most patients received only 1 or 2 botulinum toxin-A injection cycles. Our results suggest undertreatment of spasticity with botulinum toxin-A and suboptimal treatment adherence in Dutch clinical practice.

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Publication Details

Journal
Journal of Rehabilitation Medicine
Published
2026-01-15
DOI
https://doi.org/10.2340/jrm.v58.43952
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study

Thom S. Lysen, Hanne van Ballegooijen, Max van Wijk, Alexander C.H. Geurts et al.
Journal of Rehabilitation Medicine
Botulinum Toxin and Related Neurological Disorders
article

Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study

Thom S. Lysen, Hanne van Ballegooijen, Max van Wijk, Alexander C.H. Geurts, Mary Verhoeven
article en

Abstract

Claims data from a national healthcare insurance fund in the Netherlands showed that only 1.7% of patients with post-stroke spasticity received botulinum toxin-A. Botulinum toxin-A treatment doses and intervals varied widely across patients and most patients received only 1 or 2 botulinum toxin-A injection cycles. Our results suggest undertreatment of spasticity with botulinum toxin-A and suboptimal treatment adherence in Dutch clinical practice.

Journal of Rehabilitation MedicineVol. 58
Radboud University Nijmegen (NL), Radboud University Medical Center (NL), IQVIA (United Kingdom) (GB), IQVIA (United States) (US), Ipsen (Netherlands) (NL)
Ipsen
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Openalex Percentile: Top 87%
Botulinum Toxin and Related Neurological Disorders
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Real-world use of botulinum toxin-A for post-stroke spasticity in the Netherlands: a retrospective claims study — Thom S. Lysen, Hanne van Ballegooijen, et al. · Journal of Rehabilitation Medicine (2026) | TGRS Research Map | TGRS