Investigating the molecular mechanisms of glutamine metabolism and mitochondria-related biomarkers in Alzheimer’s disease through transcriptomics and experimental validation

This study ultimately identified SNCA and PPP2R1A as biomarkers for AD, providing a theoretical foundation and potential targets for the diagnosis and treatment of AD.

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Publication Details

Journal
European journal of medical research
Published
2026-01-15
DOI
https://doi.org/10.1186/s40001-025-03747-1
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigating the molecular mechanisms of glutamine metabolism and mitochondria-related biomarkers in Alzheimer’s disease through transcriptomics and experimental validation

Manxia Wang, Yuan Yao, X.C. Si, Shihan Tian et al.
European journal of medical research
Alzheimer's disease research and treatments
article

Investigating the molecular mechanisms of glutamine metabolism and mitochondria-related biomarkers in Alzheimer’s disease through transcriptomics and experimental validation

Manxia Wang, Yuan Yao, X.C. Si, Shihan Tian, Xin Li, Yudong Chen, Guode Wu
article en

Abstract

This study ultimately identified SNCA and PPP2R1A as biomarkers for AD, providing a theoretical foundation and potential targets for the diagnosis and treatment of AD.

European journal of medical researchVol. 31(1)
Xiamen University (CN), Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Good health and well-being
Openalex Percentile: Top 88%
Alzheimer's disease research and treatments
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