Comparison of the diagnostic accuracy of [68Ga]Ga-Trivehexin PET/computed tomography and [18F]FDG PET/computed tomography in nodal staging of various solid tumors

This study demonstrates that [ 68 Ga]Ga-Trivehexin PET/CT offers higher specificity than [ 18 F]FDG PET/CT, particularly in benign lymph node lesions, and is effective in accurately identifying metastatic lymph nodes. Compared to [ 18 F]FDG PET/CT, 68 Ga-Trivehexin PET/CT provides lower false-positive rates and higher diagnostic accuracy, potentially reducing the need for unnecessary invasive procedures.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2026-01-15
DOI
https://doi.org/10.1097/mnm.0000000000002109
Primary Topic
Medical Imaging Techniques and Applications
Type
article
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article

Comparison of the diagnostic accuracy of [68Ga]Ga-Trivehexin PET/computed tomography and [18F]FDG PET/computed tomography in nodal staging of various solid tumors

Serkan Kuyumcu, Nadiye Akdeniz, Halil Kömek, Fulya Kaya İpek et al.
Nuclear Medicine Communications
Medical Imaging Techniques and Applications
article

Comparison of the diagnostic accuracy of [68Ga]Ga-Trivehexin PET/computed tomography and [18F]FDG PET/computed tomography in nodal staging of various solid tumors

Serkan Kuyumcu, Nadiye Akdeniz, Halil Kömek, Fulya Kaya İpek, Berat Soylu, Dilara Denizmen Zorba, Fatih Güzel, Canan Can, Yunus Güzel, İhsan Kaplan, Ferat Kepenek, Hüseyin Karaoğlan
article en

Abstract

This study demonstrates that [ 68 Ga]Ga-Trivehexin PET/CT offers higher specificity than [ 18 F]FDG PET/CT, particularly in benign lymph node lesions, and is effective in accurately identifying metastatic lymph nodes. Compared to [ 18 F]FDG PET/CT, 68 Ga-Trivehexin PET/CT provides lower false-positive rates and higher diagnostic accuracy, potentially reducing the need for unnecessary invasive procedures.

Nuclear Medicine CommunicationsVol. 47(4)
Sağlık Bilimleri Üniversitesi (TR), Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR), Istanbul University (TR)
Openalex Percentile: Top 88%
Medical Imaging Techniques and Applications
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